Preparation of spherical agglomerates of tolfenamic acid
The purpose of the study was to prepare spherical agglomerates (SA) of Tolfenamic acid (TA) by solvent change method. Crystallization medium used for spherical agglomerates of Tolfenamic acid consisted of N,N-dimethylformamide (DMF), Water and chloroform. The presence of solvents residuals in SA was determined by Gas chromatography and particles were characterized by DSC, FT-IR, XRD and SEM. The respective solubility study and dissolution behavior studies were carried out. The samples were stored in stability chamber to investigate their physical stabilities. Residual Solvents in SAs were found to be within the limit and exhibited decreased crystallinity as well solubility and dissolution of the spherical agglomerates was improved than commercial sample of Tolfenamic acid. In stability study, it was found that physical properties and release profile of the spherical agglomeration was unaffected for 6 months. Hence this technique can be used to obtain modified drug raw material for formulation of tablets of Tolfenamic acid by direct compression with directly compressible tablet excipients.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Quantifying GoS and QoS in CDMA cellular networks
To satisfy the ever increasing network capacity, cellular systems should operate effectively with good grade of service (GoS) and quality of service (QoS). This paper proposes a quantitative approach to measuring the GoS and QoS performance of CDMA systems. It studies a realistic CDMA system operating in Nigeria and obtains empirical data from the field. A multi-dimensional Markov chain model is derived using related parameters and simulated under ideal conditions. The performance metrics of interest include blocking probability, handoff failure probability and weighted cost for GoS, and loss of communication quality for QoS. Simulation results show that effective link adaptation policies can greatly improve the system’s performance.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Quantifying the uncertainty in the development of ‘OWA’ marginal field, onshore Niger Delta, Nigeria
The development of the field was considered by running the cashflow analysis and establishing the economic indications. The one-well scenario was only able to produce 50% of EUR (2.8MMbbl) while the two-well scenario gave up to 80% EUR (4.7MMbbl) before abandonment rate for a field life of about 15 years. The cashflow analysis showed an attractive marginal project with positive Net Present Value for the $50/bbl base oil price scenario and the contractor’s take was estimated to be about 22% of the total share. The greatest effect on the NPV was seen from the Petroleum Profit Tax and the oil price in the sensitivity analysis which is negative and positive respectively. OWA marginal field reflects a typical low reserve development category and with effective cost management even at extreme low crude oil prices, a marginal profit can be ascertained and eventually fostering the Nigeria economy.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Recent Trends on Optimization Techniques, Cutting Parameters, surface integrity & Material Removal Rate in machining of AISI stainless steel: A review
Surface finish is very important criteria in Industry for quality of the product. For obtaining the desired surface finish, process parameters of machining process turning, have to be optimized. Up to now industries are dependent on Handbook data, for determining the parameters, but using Taguchi method & Response surface method, optimized data can be obtained by preparing the model, and validation of that model is done by the experiments. In the present paper, review of such effort is taken into account. This is a short review of researchers work for optimizing the process parameters using speed, feed, depth of cut, nose radius, various coating on tool, and tool geometry as input parameters and output parameter as surface roughness, tool wear, Material removal rate etc.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Relationship between occupational stress (0S) and organization citizenship behavior (OCB) of academic staff working at higher educational level
The present study was aimed to analyze the relationship between occupational stress and organization citizenship behavior of academic staff working in Higher Education Institutions of Pakistan. Qualitative and quantitative approaches have been used to explore the relationship of occupational stress and organization citizenship behavior by using a sample of 240 academic staff of public sector institutions of higher education located in Islamabad, Pakistan. Data were collected through personal visit to the offices of academic staff. Two research instruments i.e. Occupational Stress Inventory–revised (OSI-R) and OCB inventory by Podsakolf and Mackenzie were used to collect data. For data analysis Pearson Correlation was applied. Data analysis revealed that significant negative relationship was found in responses of academic staff regarding occupational stress and organization citizenship behavior.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Research on the Urbanization Paths in Ethnic Regions of China based on Eco-civilization
Economic growth is the core power to promote and shape the urbanization development, which helps to promote the economic development and social progress in ethnic regions of China Ecological civilization focuses on improving the relationship and ending the confrontation, separation, mutual exclusion and conflict between man and nature, ethnic regions of China should promote the construction of ecological civilization from multiple aspects and realize sustainable development. Xinjiang Uygur Autonomous Region is one of five ethnic regions of China; the urbanization in Xinjiang is unique in its functions, layout, dynamic mechanism, realizing path, and system background. Thus, it is necessary to select different paths according to different local conditions, to achieve multiple functions of economic development, ecological security and social stability.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Robust neuronal adaptive control for a class of uncertain nonlinear complex dynamical multivariable systems
In this paper, we proposed the development of neural adaptive controls to ensure the robustness of uncertain nonlinear multivariable systems. We used two techniques: Robust neural adaptive control and neural indirect adaptive control. The study of the stability and robustness of both techniques was performed by Lyapunov theory. To validate these techniques and discover their effectiveness, a simulation example was considered. The simulation results obtained by these two control techniques have shown the effects of disturbance compensation, good performance tracking data paths and stability control systems. Comparative studies between these two techniques show that the neural indirect adaptive control cannot mitigate the effect of disturbances compared to the robust neural adaptive control.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Secured medical image transmission using chaotic map
Image cryptography and Steganography has attracted extensive research on the security of message that is to be transmitted in the open insecure medium. This is due to the fact that huge amounts of data can be hidden without perceptible impact to the carriers and possibly because of the popularity of electronic images and medical images that have become widely available. The chaotic based secret writing has its own advantage and it is mainly based on the initial condition which is the secret key for the secret writing. The chaotic based encryption serves as the robust mechanism against all sorts of attacks. In this paper, a novel image encryption and decryption scheme is proposed. Due to sensitivity to initial conditions, chaotic maps have a good potential for designing dynamic permutation map. Here a chaotic Henon map is used to generate permutation signal. Simulation results illustrate that the scheme is highly key sensitive and shows a good resistance against brute-force and statistical attacks.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Social Trust in Iran: A Hobbesian Explanation
This article investigates social trust- trust in other citizens- and its determinants in two cities of Iran. For this purpose, a model based on institutional theory of Rothstein and Stolle (2008) and Putnam's social capital theory was designed and tested. Variables extracted from the first theory include: feeling social security, discrimination experience, attitude toward corruption and institutional trust. Variables extracted from the second theory are membership in formal groups, membership in informal groups, components of socioeconomic status (education, income and job rank), using mass media, age as well as city of residence. Through cluster sampling 1200 individuals were randomly selected to contribute to the study. The results clearly indicate that the institutional theory is stronger to explain social trust than social capital theory. That is to foster social trust in a society primarily it is necessary to control destructive factors so that nurturing factors of trust are effective.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]
Spherical agglomeration: a tool of particle engineering for making drug powder suitable for direct tabletability
Direct tabletting technique is the modern and the most efficient process used in tablet manufacturing which has been successfully used for various drugs. But the process strongly depends upon the quality of the crystals used. Spherical agglomeration, a novel crystallization technique that can transform directly the fine crystals produced in the crystallization or in the reaction process in to a spherical shape agglomerates, was developed by Yoshiaki Kawashima and coworkers in 1986. There are currently four methods to accomplish the conversion of drug particles into spherical agglomerates. Spherical agglomeration technique can transform directly the fine crystals, produced in the crystallization process into a spherical shape. Spherical agglomeration is a particle design technique, by which crystallization and agglomeration can be carried out simultaneously in one step. Spherical crystallization is a versatile process that enables to control the type and size of the crystals. Agglomerates exhibit improved secondary characteristics like flowability and compressibility. Drug release from these spherical crystals can be improved or can be controlled. This technique will be an invaluable technology in future, if it is scaled-up to manufacturing level. In this review we will discuss about the advantages, method and parameters which can be improved by spherical crystallization process. In addition current and future prospects of spherical crystallization are also discussed.
Please Login using your Registered Email ID and Password to download this PDF.
This article is not included in your organization's subscription.The requested content cannot be downloaded.Please contact Journal office.Click the Close button to further process.
[PDF]