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Mycobacterium tuberculosis, an anaerobic, acid-fast, non-motile, non-encapsulated and non-spore forming bacillus is an obligate intracellular pathogen and the etiological agent of tuberculosis (TB). Infections with M. tuberculosis results in significant morbidity and mortality globally, with an estimated 14 million individuals infected in 2007 and increasing annually. The emergence of drug resistant strains such as the multidrug-resistant (MDR), extensively drug-resistant (XDR) and totally drug-resistant (TDR) strains of M. tuberculosis poses a significant threat to the control of TB. These variations in sensitivity and resistance to different antitubercular agents by strains of M. tuberculosis are attributed to their genetic diversity and distribution in different regions of the world. This however, determines their virulence, immunogenicity, and drugs resistance and/or sensitivity pattern. The use of Molecular techniques to differentiate between strains of M. tuberculosis, the causative agent of TB is key to the understanding and characterization of resistance strains and virulence. This review will highlight and discuss M. tuberculosis, its challenges to global health sector, the emergence and spread of drug resistance, and the molecular mechanisms of the drug action and drug resistance.

The geometries, electronic structures, polarizabilities, and hyperpolarizabilities of organic dye sensitizer 1,4-Phenylenediacetonitrile was studied based on ab initio HF and Density Functional Theory (DFT) using the hybrid functional B3LYP. Ultraviolet-visible (UV-Vis) spectrum was investigated by Time Dependent DFT (TDDFT). Features of the electronic absorption spectrum in the visible and near-UV regions were assigned based on TDDFT calculations. The absorption bands are assigned to ???* transitions. Calculated results suggest that the three excited states with the lowest excited energies in 1,4-Phenylenediacetonitrile is due to photo induced electron transfer processes. The interfacial electron transfer between semiconductor TiO2 electrode and dye sensitizer 1,4-Phenylenediacetonitrile, is due to an electron injection process from excited dye to the semiconductor’s conduction band. The role of cyanine and methyl group in 1,4-Phenylenediacetonitrile in geometries, electronic structures, and spectral properties were analyzed.

We are very happy to announce that from 4th July 2018, Mr. Rudy F. Daling, Maed has joined the team of Elixir Editorial Advisory Board. He/She will carry a special responsibility for dealing with manuscripts based on Educational Management. The appointment Mr. Rudy F. Daling, Maed as member Editorial Advisory Board strengthens the links and will make it easier for prospective authors to establish contact with the journal. Please send any expressions of interest to elixirpublishers@gmail.com.

Carbon nanotubes fluorescence in a region of the near-infrared, where human tissue and biological fluids are particularly transparent to their emission, but especially in the last decade it has attracted scientific and economic interest triggered by a rapid increase in response to specific biomolecules. A suitable scheme to conjugate the drug and the nanotube is required to make CNTs into viable delivery vehicles. In this present work, multi walled carbon nanotube decorated with titanium dioxide (TiO2-MWNTs) particles have been synthesized and employed as acceptor type materials in organic bulk heterojunction. The donor type material employed in the blend was regioregular poly (3-Octyl Thiophene) (RR-P3OT). X-ray diffraction (XRD), UV-Visible spectroscopy, FT-IR spectroscopy and scanning electron microscopy (SEM) characterized and analyzed.

A dual-band characteristic of multilayer aperture coupled microstrip log-periodic dipole antenna is studied. Further loading of patches is performed and its effects are investigated. It is a probe fed antenna for impedance matching with 50? coaxial cable. This antenna works well in the frequency range 4.3 GHz to 8.5 GHz. It is basically a low cost, light weight medium gain antenna, which is used for wireless communication. The multilayer microstrip antenna structure involves addition of multiple layers one over the other. When a microstrip antenna is stacked with a superstrate dielectric layer, its properties like resonance frequency, gain and bandwidth are changed, which may affect the system performance. With proper choice of the thickness of substrate and superstrate layers, significant increase in bandwidth and return loss can be achieved for practical applications. This structure uses stacked configuration of three different substrates. One dielectric substrate as a feeding plane, one dielectric substrate as aperture plane and a dielectric substrate as a LPDA. The simulated antenna yields -29.16 dB return loss with 33% bandwidth with a size of 24x26x6mm3. The proposed antennas present an excellent candidate for compact and low-cost microwave integrated systems.

There are number of postcolonial theorist and critics such as Frantz Fanon, Homi K. Bhabha, and Gayatri Chakravorty Spivak contributed to postcolonialism and the postcolonial intellectuals has developed a new perspective whereby the conditions of marginality, subalterneity, plurality, mimicry, hybridity are seen as sources of energy and potential change. Many women writers, thinkers and critics have formulated a school of thought that searches for such instances in literature. Feminist literary criticism primarily responds to the way woman is presented in literature. Postcolonial feminist criticism examines how women are represented in colonial and postcolonial literature and challenges assumptions which are made about women in both literature and society. Postcolonial feminists point out the ways in which women continue to be stereotyped and marginalised, ironically sometimes by postcolonial authors who might claim to be challenging a culture of oppression. The main task of the feminist literary critics seems to oppose patriarchal norms which exist in the society. The marginalizations of women, their predicament, struggle for identity, finding their own space, celebrating the female body are the chief subjects of this trend. The protagonists of all the novels of Manju Kapur are seen as women struggling against all odds. Manju Kapur has always tried to depict the picture of the sufferings of women at deeper level in her novels. In her novels, she deals with the problems of women and their struggle to establish an identity. She in particular takes up the cause of the females who are victimized on account of conservative and traditional mind-set of the Indian masses. Most of the protagonists of Kapur are women who assert their rights and raise voice against male chauvinism. Nina is one such character who rebels against the exploitation and oppression to assert her individuality.

This paper serves as a platform to discuss and bring out the concept of kernel, separation axiom and continuity of ?gb+ and ?gb+ -closed sets, under the light of simple extension topological spaces.

On the electrodynamics of moving bodies by Albert Einstein is based on Trickeries (Open letter to Professors, Teachers, Researchers and Students of Physics)

Information criterion, KIC, for the model selection based on kullback-leibler risk symmetric by cavanagh, be present for large sample. KIC as an asymptotically unbiased estimator kullback-leibler risk symmetric, is consider divergency between the true model and the candidate model. It is an inconsistent information criterion. All the criteria that exsist based on kullback-leibler risk (symmetric or asymmetric)are inconsistent. In this article based on information criterion KIC is defined consistent information criterion, MIC. This criterion, MIC also is made based on kullbake-leibler symmetric. At the end these two information criteria for linear regression models has been consider by simulation monte carlo.

Ware house Optimization process are based on modern warehousing and multi-optimization models. Modern warehousing become more typical and complex to handle and this paper highlight the role of operational and technical solutions in the development of today warehousing projects Warehousing optimization studies can be undertaken on the basis of its technical structure and operational framework or its controlling system. Present paper reveals the hurdles and complexities of modern warehousing optimization and also focus on remedies to overcome the constraints in optimization of warehouse. Warehouse management encompasses the planning and management of all activities involved in handling, storage and procurement, conversion, and all logistics management activities. Importantly, it also includes coordination and collaboration with channel partners, which can be suppliers, intermediaries, third-party service providers, and customers. The optimal operation of a warehouse is achieved when each customer is satisfied completely and logistic processes are done within a reasonable timeframe with minimum cost and optimal utilization of resources under dynamically changing conditions. This paper also reveal that the effective use of space within the boundary of warehouse provide the basic platform to solve the problems coming across in the warehouse management. The stability of using steel storage racks depend upon solely on the pallet beam to upright connectors and on the stiffness of base plate to floor connection.