Physiology and Anatomy

The intradiverticular bladder carcinoma (IDUCB) is a rare and poorly known entity. To analyze diagnostic and therapeutic features of urothelial carcinoma within the bladder diverticulum. Twenty eight men with an average age of 65 years were included. The main reason for consultation was hematuria. The intradiverticular tumor was suspected by radiological assessment in 11 patients. All these patients underwent an endoscopic resection of the tumor. The histological study concluded to a pTa stage in 10 patients, pT1 stage in 11 patients and invasive tumors in 7 patients. A complementary endovesical BCG-therapy and cystoprostatectomy were performed in patients depending on the stage, grade, recurrence and multifocality. With an average follow-up of 31 months, seven recurrences were found in the group of superficial tumors, including 5 cases of progression to invasive stage and 2cases of nodes invasion. Intradiverticular bladder tumors are rare and more common in elderly. They are distinguished from conventional bladder tumors by a triple specificity: pathological specificity with high frequency of ?T3a tumor, diagnostic specificity with a risk of under-staging of the extent and tumor multifocality, therapeutic specificity linked to a worse prognosis than conventional tumors which encourages a strict limitation of the indication of conservative treatment.

The incidence of neurodegenerative diseases are increasing in the present generation. Based on their diversified causes it is targeting almost all the age groups including young (juvenile) and old (senile) population without discrimination. There are some metabolic diseases which are targeting the brain functions in young. The juvenile diabetes is one among them, where the excess of unutilized glucose is following wide range of deranged paths resulting into encephalopathy. The early detection of such diseases needs to be identified and tackled at the earliest. The existing modern treatment is having much limitation; hence it is inviting the contribution from the field of alternate herbal medicine.

The invasion of the orbit with metastatic tumors is rare. In addition, some cases of unilateral metastatic disease have been reported but more often it is bilateral involvement. Moreover, it frequently attends locoregional invasion of the orbit by tumors adjacent structures including intraocular tumors in children. In adults, the orbital metastases are mostly of epithelial origin and they are considered a full metastatic site [1, 2, 3, 4, 5, 6]. In the literature, many cases of orbital metastases have been reported, such as esophageal cancer metastasis [7], breast [8], pancreatic [9] as well as lung [10]. Today, metastatic carcinoma of the orbit are 2.3 to 7% of orbital tumors [11, 12]. Cancer of the prostate is the most common cancer in humans outside of skin cancer, and it often leads to bone and visceral metastases. [13] However, the orbital metastases appear at an advanced stage of the disease [3, 4]. The purpose of this article is to report the case of a bet diagnosed with adenocarcinoma of the prostate revealed a metastatic orbital tumor.

Isolation of the right subclavian artery occurs when the right subclavian artery takes origin from the pulmonary artery through a ductus arteriosus. The right subclavian artery normally takes origin from the brachiocephalic trunk, specifically the brachiocephalic artery, however due to this anomaly it takes origin from the pulmonary trunk, specifically the right pulmonary artery. As a result of this aortic arch malformation, there is a continuous filling of blood of blood into the right pulmonary artery; this phenomenon is known as subclavian steal phenomenon. As blood continues to flow in the right pulmonary artery, it gives rise to other complication s such as pulmonary over circulation.

The term exstrophy-epispadias is mainly coined due to the group of congenital abnormalities such as, bladder-exstrophy and cloacal-exstrophy. Because of the presence of abnormal opening into the cloaca, all embryos were considered by an abnormal widening of caudal trunk at the level of the leg buds which, in the youngest embryos, was associated with the abnormal presence of large aneurysmatic swellings of the dorsal aortae at this side.

Soft tissue tumors, benign or malignant, are often seen and diagnosed at a stage they become clinically gigantic or when traditionnal treatments undertaken prove their unefficiency. Authors wanted to illustrate this fact by relating the observation a giant lipoma of the thigh. The authors report in this study the observation of a 48 year old patient with a painless swelling of the left thigh evolving for 35 years and gradually increased in size, without repercussion on the function or the General state. Palpation founds a tumor in the anterolateral region of the left thigh. Radiography shows the shadow of the tumor with bone integrity. For reasons of lack of resources, MRI could not be done. Histology confirmed the diagnosis. A giant lipoma of 2900 grams measuring 27x18 cm.anatomopathology reconfirms the diagnosis.

In this paper, Periodic Component Analysis is used to extract the fetal electrocardiogram (ECG) from the abdominal and thoracic maternal electrocardiogram. The thoracic ECG (TECG) is assumed to be almost completely maternal while the abdominal ECG (AECG) is considered to be composite as it contains both the maternal and fetal ECG signals. Three channels of signal, from chest leads and five from abdominal leads from DaISy data set are used . Extracted signals consist of mixture of components including maternal ECG, fetal ECG and random noise. Periodic Component Analysis (?CA) is used to isolate the fetal ECG from maternal ECG signal. Generalized Eigen Value Decomposition is used to decompose the ECG record. It uses phase-wrapping of the R-R interval, for extracting the most periodic linear mixtures of a recorded dataset. Comparison with Independent Component Analysis (ICA) demonstrates the quality of this method. This method is therefore of special interest for the decomposition of ECG and the extraction fetal ECG from maternal ECG signal. The average sensitivity and accuracy of this method is 99.04% and 94.56% respectively. By using one thoracic signal and three abdominal signals this method is able to achieve 100% sensitivity and accuracy.

The hydatid cyst of the spleen is a rare affection. The location splenic comes in 3rd position after the liver and lungs. In the absence of really effective medical treatment, splenic hydatid disease often leads to surgery. We report the case of a patient with calcified splenic hydatid cyst discovered incidentally and in whom the therapeutic decision was abstention and monitoring.

To specify the types of statistical methods, currently most influencing high-quality surgical research, we systematically reviewed original research articles published in The American Journal of Transplantation, Annals of Surgery, Liver Transplantation and The American Journal of Surgical Pathology. We further aimed to determine complexity of data analysis in these journals. Of 518 papers reviewed, 74.7% (95%CI 70.7-78.4) contained methods of inferential statistics. Most frequently used inferential methods among all journals, were basic contingency table analysis, including c²-tests and Fisher’s exact tests, and methods of survival analysis, with observed frequencies of 39.6% (95%CI 35.3-43.9) and 30.7% (95%CI 26.8-34.9), respectively. Other commonly used procedures were nonparametric techniques and t-tests. Complexity of data analysis was rather sophisticated in The American Journal of Transplantation, Annals of Surgery and Liver Transplantation, with more than 50% of papers using advanced statistical techniques. However, nearly 65% of papers from The American Journal of Pathology were purely descriptive, without any analytical power. Our results indicate that more emphasises should be given to the magnitude of treatment differences and to statistical estimation techniques than to solely rely upon uncritical significance testing. Moreover, authors should be encouraged to further utilize new statistical methodology in their research.

Choanal atresia is a rare congenital condition caused by persistence of the buccopharyngeal membrane during the development of embryo. It is characterized by the closure of posterior nares in the nasal cavity. The condition is well managed with an oropharyngeal airway. A 120 degree nasal endoscope and CT are used in the diagnosis of choanal atresia. The definitive treatment for this upper airway obstruction is surgery. The less invasive approach is the transnasal one which is the first-line approach currently. If this approach is failed transpalatal approach is proceeded which is highly invasive.