Archives-J 

Microchip drug delivery system is the most wonderful system of delivering the drug for a great span of time without the intervention of the patient to whom it is fixed. it consists of varied number of sockets containing drug (generally ranging from 50-300) which release the drug at the fixed intervals each at a time. Microchips has developed its core technology for drug delivery by hermetically sealing small quantities of drug in the microreservoirs, and releasing that drug on schedule or demand. In drug delivery, there are several fundamental challenges: Long-term storage and protection of the compound, Appropriate delivery (i.e., timing and pharmacokinetics), Release of precise amounts of a compound at desired interval Compliance to prescribed therapy. A microchip system has the ability to store a large number of drugs or chemicals, control the time at which release begins, and control the rate at which the chemicals are released. Drug delivery device is capable of controlled, pulsatile or continuous release of a wide variety of drugs that can be safely implanted inside the body. The microchip could be integrated with a tiny power supply and controlled by a microprocessor, remote control , or biosensors.

Since candida inhabits both diseased and normal healthy human population its carriage rate signifies while interpreting the microbiological results associated with candida. In this study oral swabs were collected from the type II diabetic and non-diabetic individuals and the collected specimens were subjected to direct microscopic examination and culture on sabouraud dextrose agar (SDA). The microscopic and culture results had shown difference in these two different study subjects. Compared to non diabetic individuals the oral swab of type II diabetic individuals had shown increased carriage rate of candida. It revealed the facts of the candida colonization among type II diabetic individuals. From this study results it came to understand that the hyper glycemic condition of the type II diabetic patients could be the major reason for the colonization of candida. Candida is a yeast which can attack both immuno compromised and immuno competent humans. Further it needs health care professionals attention to take care of these population.

In this short search, we will prove the mathematical fact that all the even integers are equals that equal to zero. And all the odd integers are equals that equal to One, Through simple numerical proof as we shall see below.

In today's competitive world, organizations are expected to surpass the competitors and benefit from the resources and benefits. Therefore, organizations need to improve the current performance is felt more than ever that this requires to identify organizational optimal strategies, and consider all strategies simultaneously. In this study, to enhance competitive advantage and according to customer requirements, alignment between business, production and marketing strategies, House of Quality (QFD) approach has been used and zero-one linear programming model has been studied. First, the alignment between production and marketing strategies with business strategy, independent weights of these strategies is calculated. Then with using QFD approach the aligned weights of optimal strategies in each production and marketing field will be obtained and finally the aligned marketing strategies selection with the purpose of allocating budget and specialist human resource to marketing functions will be done that lead to increasing competitive advantage and benefit.

In this paper, a mathematical model is proposed to study the effect of the depleting dissolved oxygen on the existence of interacting planktonic population. The mathematical model is formulated using the system of nonlinear ordinary differential equations. The model includes four state variables viz., nutrient concentration, density of algae, and density of the zooplankton population and concentration of dissolved oxygen. All the feasible equilibria of the system are obtained and the conditions for the existence of the interior equilibrium are determined. The local stability analyses of all the feasible equilibrium points are obtained. The non-linear stability analysis of the non trivial equilibrium point has been carried out and the criteria for the survival or extinction of the species have been obtained with numerical simulation.

A Study on moisture management properties for Polyester with Bamboo Biply knitted fabrics has been reported. The polyester (80 D), Bamboo yarn (30s and 40s Ne) were selected to produce the Biply rib knitted fabrics with various areal density, thickness and tightness factors to analyze the moisture management properties of fabrics. It was observed that polyester with bamboo Biply knitted fabrics have higher air permeability than the polyester with cotton Biply knitted fabric. It is also observed that there is a significant difference between water vapour permeability of polyester with bamboo and polyester with cotton Biply knitted fabrics. It is also found that the polyester with bamboo knitted fabric has better wicking rate than the polyester with cotton Biply knitted fabrics. This Polyester with Bamboo Biply knitted fabrics materials can be used to prepare the composite materials.

This study carried out the morpho-agronomic characterization and nutritional analysis of 9 cultivars of sweet potato (Ipomoea batatas L.) in Kisangani, Democratic Republic of Congo. The experimental design was that of randomized blocks, comprising 9 treatments of sweet potato cultivars (Carrot, Damu, Elengi, Mugande, Muganderva, Monde, Mambokolo, Kandolo and Kilomo) and 4 replications. The treatments were installed on ridges of 2.5 m length and 0.5 m width. It was obtained, the cultivars with tuber of pink color (Mambokolo, Kilomoya, Elengi and Monde); light green (Kandolo, Damu); white of diamond (Mugande); chocolate with coverage of the ground by the biomass is total for the cultivars Elengi, Mungade and chocolate (Mugande) and beige (Carrot). The shapes of the leaves, round (Mambokolo); obovate (Kandolo, Elengi); elliptic (Damu, Kilomoya); oval (Mugande) and irregular (Carrot, Muganderva and Monde). As for the unit weight of the tubers, the cultivars Mambokolo (3.35kg) and Elengi (3.5kg) performed well at 5 months of cultivation and the nutritional parameters showed that the cultivars Elengi, Kandolo and Carrot are richer in crude protein respectively 4.56; 1.43 and 0.75%.

To present an unusual case of Multiple primary malignant neoplasms and to describe the steps we followed to evoke each diagnosis trying to reveal an underlying genetic disorder and to discuss the best strategy of treatment of our patient. We describe the work-up, diagnosis, and treatment course of a 50-year-old woman who presented with papillary thyroid carcinoma, parathyroid adenoma, pulmonary adenocarcinoma and pheochromocytoma. The tumor involvement of the parathyroid and the adrenal gland led us to think about NEM2 syndrome. Instead of medullary thyroid cancer which is invariably present in NEM2 syndromes, our patient presented a papillary thyroid cancer. We could think that the total thyroidectomy that have been performed in our patient could have prevented the appearance of a medullary thyroid carcinoma. The possibility of carrying out a DNA sequencing with research of germline RET mutation could have been very interesting to determine if this case can be considered as an unusual MEN 2A syndrome. Tumor DNA sequencing has a major role to determine molecular characteristics in different tumors and research eventual common biomolecular abnormalities, which can provide a genetic counseling.

Studies on species diversity of Ophidians are less advanced in the Central Congo forest ecoregion than in other ecoregions of the central Congolese basin. In other words, the diversity of Ophidians in this region remains poorly known. Preliminary research indicates that the central Congolese basin harbours remarkable diversity of Squamates (Lokasola & al. 2017), but this remains to be confirmed by updated studies on snakes, a group that has been little studied in the sector. The most extensive study of the herpetofauna of this area dates from the colonial period, conducted by Schmidt (1919). It is now obsolete (Lokasola & al. 2017, Lokasola, 2022). Therefore, the present article examines the diversity of Ophidian species in the Lokutu square degree, with the objective of producing a species list and reporting their ecological preferences, conservation status, and the harmfulness of their bites. The main aim is to test the hypothesis that the species list of snakes presented by previous studies on the sector is incomplete. To achieve this objective, a team composed of four people (Felix Kihambu, our dissertation supervisor, and two local guides) conducted surveys across a range of habitats within the Lokutu square degree. The habitats studied included forests, wetlands, rivers, and agricultural lands. The studies were conducted both during the day and at night, to maximise the chances of encountering both diurnal and nocturnal species. Collections were carried out randomly on reconnaissance trails and were time-limited to obtain semi-quantitative binary presence/absence data. A total of 31 snake species were reported, thus adding ten species to the twenty or so already known to exist in this sector. Although still short of the forty species expected based on predictions rooted in the continuity of the Congolese equatorial forest and the absence of biogeographical barriers for snakes, our results are highly significant as this is the first time the threshold of 24 species has been surpassed in this sector. We recommend further systematic studies using genetic markers and more extensive sampling of certain taxa to gain a more comprehensive understanding of the subject.

This study presents a novel natural convection process. A prototype of an indirect solar dryer, with its collector made of hemispherical concentrators had been realized and studied with the idea of obtaining higher temperature in the drying chamber, and this with a steady non tracking collector. The patented collector is based on the hot-spot theory. Measurements had been conducted for all critical period of the year. The result seemed conclusive with temperature improvement in steady non tracking collectors, and suggests further investigation of the hot-spot theory, by conceiving a mathematical model and by deepening the experiment outcomes for a best thermodynamic study.