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We are very happy to announce that from 6th August 2011, Prof. Feng Ping has joined the team of Elixir Editorial Advisory Board. He will carry a special responsibility for dealing with manuscripts based on Infectious Disease. Prof. Feng Ping is currently working as Vice Director, at Department of Infectious Disease of West China Hospital, Sichuan University, P.R. China. The appointment of Prof. Feng Ping as member Editorial Advisory Board strengthens the links and will make it easier for prospective authors to establish contact with the journal. Please send any expressions of interest to chiefeditor@elixirjournal.org. Sincerely Editor-in-Chief

This project provides information about energy system by the use of bio gas... Biogas contains primarily CH4 with the balance being mostly CO2 and a small amount of trace components. Now a day’s alternate fuel appears during possessions, by better understanding its components, biogas can be processed and utilized in a more efficient, cost-effective way because of reducing fuel cost, demand of fuel, and emission influence in global warming. The most important of this work is, to produce bio gas from organic waste and reduce the usage of petrol fuel. The increase in population leads to depletion of diesel fuel. Another reason is instead of disposing the organic waste in landfill, this can be converted into a useful product (bio-gas). The bio gas can be stored in a cylinder and be placed in a luggage side box of a vehicle. A regulator is fixed on the top of the cylinder. A hose tube from a vacuum kit which is placed beneath the seat is fixed to the cylinder, so that the gas can be passed to the carburetor. The needle of the carburetor is taken out and the gas would pass on the engine directly. The air filter is partially closed in the vehicle. On kicking the bio gas from the cylinder easily pass on from vacuum gas kit to engine. A spark plug which is above the engine is used to burn the biogas. In this manner, bio gas can be used run the vehicle. The pickup and efficiency is more comparing the existing system of the vehicle has not been reduced by using bio gas. A two Stroke Petrol engine is used for this project, 2 Kg Cylinder is used. It gives 110 kilo meter for one liter of bio gas. So that it can be used in the presented vehicle without any modification. So, the compression ratio of the engine is also high 15:1 Due to high compression ratio power developed by the engine is also high. By less consumption of the fuel, the power produced is more. Petrol produces more toxic gases like HC, CO etc...But we find that methane is less toxic, and emission is very less eco-friendly compare to petrol. It makes “GREEN EVOLUTION”.

In the present study fulvic acids (FAs) were first isolated from fulvic water (FW) and fulvic urea (SU) and then their quantification was accomplished by spectrophotometric methods. Aqueous solutions of FAs, FW and SU were made at pH 7.0 in the visible wavelength region at 25 oC using calibration curve method. Plot of absorbance Vs concentration of FAs at fixed wavelength (424 nm) was linear up to 120 mg L-1. The calculated FAs concentrations were in reasonable agreement with the gravimetric estimation made by solvent extraction.

In a mobile ad hoc network, the mobility and resource constraints of mobile nodes may lead to network partitioning or performance degradation. Several data replication techniques have been proposed to minimize performance degradation. Most of them assume that all mobile nodes collaborate fully in terms of sharing their memory space. In reality, however, some nodes may selfishly decide only to cooperate partially, or not at all, with other nodes. These selfish nodes could then reduce the overall data accessibility in the network. In this paper, the impact of selfish nodes in a mobile ad hoc network from the perspective of replica allocation is examined. A selfish node detection algorithm was developed that considers partial selfishness and novel replica allocation techniques to properly cope with selfish replica allocation. The conducted simulations demonstrate the proposed approach outperforms traditional cooperative replica allocation techniques in terms of data accessibility, communication cost and average query delay.

Two thousand three hundred and seven fish specimens sampled from Nwaniba (Ikpa River) for 12 calendar months (March 2009 – February 2010) comprised 11 orders, 34 families, 59 genera and 136 species. There was temporal and seasonal significant differences (P<0.05) between number and species of fish caught. The mean annual Index of Preponderance (IP %) values ranged from 0.01 in Brienomyrus brachyistus and Periophthalmus barbarus to 4.24% in Oreochromis niloticus. Mean monthly occurrence shows highest in August (536; 23.23%) and lowest in June (47; 2.03%). The contributions of the fish orders in theirdescending order of abundance are as follow: Siluriformes (1072; 46.47%), Ophiocephaliformes (626; 27.13%), Characiformes (264; 11.44%), Mormyriformes (159; 6.89%), Clupeiformes (87; 3.77%), Cypriniformes (40; 1.73%), Gonorhynchiformes (33; 1.43%), Osteoglossiformes (13; 0.56%), Elopiformes (9; 0.39%), Pleuronectiformes (3; 0.13%) and Perciformes (1; 0.04%). The most abundant family and species in terms of number are Schilbeidae (646; 28.00%) and Parailia pellucida (577; 25.01%) while the least are Scaenidae, Soleidae and Sphyraenidae (1; 0.04%). The most abundant family in terms of species is Mormyridae (17) and the least are 9 families with only species. Relative abundance is higher during the wet season (105 species; 77.77%) than dry season (93 species; 68.88%). The largest fish size in terms of length is recorded in Chrysichthys aluuensis (45.60cmTLmax; 18.40±9.0cm) while the smallest individual is Parailia pellucida (1.10cmTLmin; 7.50±1.20cm). The overall weightiest fish is also Mugil cephalus with a total weight of 662.80gWTmax; 54.42±16.75 while the lightest individuals are Parailia pellucida and Eutropius buffei (1.00gTWmin). Previous results differ from these; which may be occasioned by the human anthropogenic perturbations which are on-going in the river system, thus leading to environmental degradation. Hence, recommendations are proffered.

A simple, accurate, rapid and precise isocratic reversed-phase high-performance liquid chromatographic method has been developed and validated for simultaneous determination of Amlodipine, Atenolol and Hydrochlorothiazide in capsules. The chromatographic separation was carried out on an cosmosil packed column 5C18-MS-I I analytical column (250×4.6 mm; 5 ?m) with a mixture of Phosphate buffer:Acetonitrile:Methanol pH 6 adjusted with Ortho phosphoric acid (30:20:50, v/v) as mobile phase; at a flow rate of 1 ml/min. UV detection was performed at 240nm. The retention times were 2.637, 3.148 and 8.492min. for Hydrochlorothiazide, Atenolol and Amlodipine respectively. Calibration plots e linear (r2>0.998) over the concentration range 2-12µg/ml for Amlodipine , 10-60?g/ml Atenolol and 2-12µg/ml for Hydrochlorothiazide. The method was validated for accuracy, precision, specificity, linearity, and sensitivity. The proposed method was successfully used for quantitative analysis of capsules. No interference from any component of pharmaceutical dosage form was observed. Validation studies revealed that method is specific, rapid, reliable, and reproducible. The high recovery and low relative standard deviation confirm the suitability of the method for routine determination of Hydrochlorothiazide, Amlodipine and Atenolol in bulk drug and capsule dosage form.

PbS_xO_1-x (x = 0.0, 0.2, 0.4, 0.5, 0.6, 0.8 and 1.0) nanocomposites were prepared by the microwave assisted solvothermal method using a domestic microwave oven for the first time. The yield percentage and the preparation time were noted. The samples were annealed at 200 ^oC for 1 hr to improve the ordering.  Grain sizes and lattice parameters were determined by carrying out X-ray powder diffraction measurements. AC and DC electrical measurements were carried out on palletised samples at various temperatures ranging from 40-150 ^oC.  Results of the present study reveal that the space charge contribution plays a significant role in the charge transport process and polarizability in all the seven nanocrystals studied. The electrical parameters increase with increasing temperature. Results of the present study reveal that the space charge contribution plays a significant role in the charge transport process and polarizability in all the seven nanocrystals studied.

The present work is concerned with the synthesis and the structural elucidation of the two ligands, viz., 2-thio picolinamide (TPA) and 2-N-benzyl TPA. The isolated solid complexes are subjected to characterised by Wet chemical analysis (N, S, metal), Conductivity measurements, Infrared including far infrared spectral measurements and H¹ NMR, and Mass spectral measurements.

4-chloroaniline reacts with 1-(4-hydroxyphenyl)-ethanone in presence of 1-napthonicacid and copper metal as a catalyst gives 1-(4-(4-aminophenoxy) phenyl)ethanone, which on further condensation with 4-nitrotoluene-2-sulfonyl chloride gives N-(4-(4-acetylphenoxy)phenyl)-2-methyl-5-nitrobenzenesulphonamide. This derivative react wit various substituted aldehydes to give corresponding substituted chalcone derivatives (N-1). Now these derivative (N-1) on condensation with NH2CONH2 in presence of dilute HCl gives2-methyl-5-nitro-N-(4-(3-(2-oxo-6-phenyl-1,2,5,6-tetrahydropyrimidin-4yl) phenoxy)phenyl)benzenesulfonamide (N-2). Structure elucidation of synthesized compounds has been made on the basis of the elemental analysis, 1H NMR spectral studies. The antimicrobial activity of the synthesized compound has been studied against the species Bacillus subtillis, Staphylococcus aureus, Escherichia coli and Salmonella typhi.

Fast strides are being taken by the pharmaceutical industries and the academics the world over, in research related to recent advances in designing of static diffusion cells to assure batch-to-batch drug release equivalence for semisolid dosage forms and to facilitate an easy performance of quality control tests for semisolids dosage forms. Till today, there are no pharmacopoeial methods recommended to carry out in vitro release tests for semisolid dosage forms and about selection of diffusion cells. Majority of published transport studies, particularly for skin permeation, involves the use of FDC (Franz diffusion cell). Franz diffusion cell is the only existing device recommended both by FDA (Food and drug administration) and OECD (Organization for economic co-operation and development). Unfortunately this device suffers from several limitations such as formation of air bubbles, limited receptor compartment volume, laborious and large variation among experiments. To overcome the above limitations of Franz diffusion cell, several novel diffusional cells were invented like modified Franz diffusion cells, Keshary-Hein cell, Enhancer cell, United States of Pharmacopeia (USP) - 5, 6, 7 apparatus, automatic sampling Kelder cell, Insertion cell and Plexiglas cells etc., but each invented novel diffusion cell encountered other limitations. So until date, there is no widely accepted static diffusion cell recommended by any Pharmacopeias. The primary focus of this review makes an effort to compile some of the related recent findings and highlight some of the major issues related to various diffusion cells developed till today, their comparative assets and limitations.