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The present study was to develop once-daily extended release tablet of Lamotrigine, an Anticonvulsant. It is a phenyl triazines derivative showing effective anti-convulsant properties mainly used in effective in preventing seizure spread in the maximum electroshock (MES). The tablets were prepared by the wet granulation method.. The aim of the current study was to develop and optimize a simple matrix system of the model drug (BCS Class-II) using minimum possible excipients, to release the drug in a controlled fashion.Core tablets of model drug (F1 – F12) were successfully prepared by direct compression method, Mannitol SD200 & different grades of HPMC, Xanthan gum, Surelease and Magnesium stearate as excipients by direct compression method. The F11 formulation is the best formulation out of 12 formulations, the F11 contains HPMC k4m and metalose polymers, they maximum drug release and it follows Higuchi model

Present study deals with the isolation of lipolytic lactic acid bacteria from camel milk. Bacterial lipase is secreted extracellular and hydrolyses acyl glycerides into free fatty acid. Thus, the intake of bacterial lipase directly in food sample or as probiotic formulation can be helpful for those people suffering from health implications related to high serum triglyceride level. For this purpose, a lipolytic bacterial strain Enterococcus durans purified from camel milk employing enrichment and selective culture technique. Identification was done by sequencing of 16S rDNA/D1/D2 domain of LSU rDNA or ITS region and BLAST analysis. Strain showed significant lipase activity of 3988 U/ml. Physicochemical characterization showed that optimum lipase activity was observed between 7.2-7.5 pH, 30o C – 40 o C temperature, 3.5 %- 4.5 % salinity and 4 % (v/v) inoculum’s size whereas presence of peptone, calcium and tributyrin in media enhanced the lipase production. Optimization of lipase production was done using RSM model. Further purification via DEAE anion exchange leads 1.9 fold purification of lipase with retention of 81 % lipase activity. Quality assurance of this bacterial strain as a probiotic and subsequent formulation development can be useful achievement in the field of medical microbiology.

The roots of common beans ( Phaseolus vulgaris) were collected fresh by uprooting carefully from a garden soil in Bori, in Khana Local Government Area, Rivers State, Nigeria. The root nodules were prepared using the Gwyn and Handelsman,(1989) technique, and analyzed by the spread plate method upon Yeast Mannitol agar, for the Isolation and Identification of nitrogen fixing bacteria (Rhizobium), obtained from the leguminous plant. Rhizobium japonicum, R. leguminosarum and R.aggregatum were isolated and identified. Rhizobium japonicum and Rhizobium leguminosarum were the most regular isolates, whereas, Rhizobium aggregatum were scarcely isolated. The frequency of occurrence of the microbial colony forming units were in order of 6.7, 20, 26.7, 33.3 and 13 for the sample plates,T1, T2, T3, T4 and T5 as assay of root nodules formicrobial concentration of isolates were found, in the legume plant.

The present study investigated the relationship between creativity and John Holland's personality types and views other scholars envisioned the Dutch Personality Questionnaire was used to secure paper, the relationship between creativity and personality types theory John Holland's creative personality types to compare the theories of John Holland is checked. The relationship between students' creativity with John Holland's theory of personality types must be examined to determine the relationship between two variables is creative personality types and which have higher. The statistical population included all male high school students in Kermanshah city In the case of simple random sampling - A sample of 300 participants was regular a few steps Abide creativity test to measure creativity and John Holland used to measure personality types of tests were carried out and the obtained data were processed by SPSS software. The field study is correlational research method. Statistical methods used in this study was the chi-square test because of a nominal variable and the one-way analysis of variance was used to test the hypothesis.

Table of contents for the month of February 2013

Black pepper and white pepper are made from the Piper nigrum plant. Black pepper is ground from dried, whole unripe fruit. White pepper is ground from dried, ripe fruit that has had the outer layer removed. The black pepper and white pepper powder are used to make medicine. People take black pepper for stomach upset, bronchitis, and cancer. They take white pepper for stomach upset, malaria, cholera, and cancer. Black pepper is sometimes applied directly to the skin for treating nerve pain(neuralgia) and a skin disease called scabies. Black pepper and white pepper are also used topically as a counterirritant for pain. In foods and beverages, black pepper, white pepper, and pepper oil (a product distilled from black pepper) are used as flavoring agents. Many people are ignorant about the numerous health benefits of black pepper. It contains potent antioxidant, antibacterial, anti-inflammatory and anti-carcinogenic properties. It contains iron, potassium, manganese, vitamin C and fiber in large quantities. However, beside these, it does contain other nutritional components.

The present study was carried out to analyze the use of motivational strategies at secondary level in public and private sector schools. For data collection, two schools in public and private sector each were selected from Islamabad. Data was collected through a Questionnaire. Fifty teachers (twenty-five from public and twenty five from private sector) of secondary classes were selected for answering the questionnaire. Quantitative analysis method was used for data analysis. The result of analysis shows that application of motivational strategies is better in private school as compared to public school.

We are very happy to announce that from 4th April 2015, Mr. Amjed Mirza Oda has joined the team of Elixir Editorial Advisory Board. He will carry a special responsibility for dealing with manuscripts based on Noise and Chemistry. Mr. Amjed Mirza Oda currently working as Faculty Member, Department of General Science, College of Basic Education, University of Babylon, Iraq. The appointment of Mr. Amjed Mirza Oda as member Editorial Advisory Board strengthens the links and will make it easier for prospective authors to establish contact with the journal. Please send any expressions of interest to elixirpublishers@gmail.com.

We are very happy to announce that from 10th May 2013, Mr. Hadeel Fadhil Farhood Al Joborae has joined the team of Elixir Editorial Advisory Board. He will carry a special responsibility for dealing with manuscripts based on Community Medicine. Mr. Hadeel Fadhil Farhood Al Joborae is currently working as Department of Family and Community Medicine, College of Medicine, Babylon, Iraq. The appointment of Mr. Hadeel Fadhil Farhood Al Joborae as member Editorial Advisory Board strengthens the links and will make it easier for prospective authors to establish contact with the journal. Please send any expressions of interest to elixirpublishers@gmail.com. Sincerely Editor-in-Chief

To attain large information rates, multi user detection (MUD) is a well-built aspirant for the downlink of cell phone communications. However, while transmitting any signal over fading channel, the performance of any system is highly affected. For that reason, Multiuser detection (MUD) and channel estimation play a significant function for overcoming the interference and characterizing the channel. In previous cases, this is developed by using many kinds of algorithms. But in this Paper BPSK modulation technique was introduced for multiuser detection due to the drawbacks of those algorithm. The objective of this BPSK modulation is used to minimize the error rate of the user transmitting signal. In this, the user detection complexity and the interference of user transmitting signal are resolved. Since the detection complication and the required time are concentrated. In general, we make use of many types of filters namely, linear filters, nonlinear filters etc. here we are going to implement with adaptive filters. By using nonlinear filters we get narrow bandwidth responses and by using linear filters we get interference and BER is also high. So by using adaptive filters we overcome these drawbacks. The goal of adaptive filters is to improve synchronization and capacity by reducing interference between users. Adaptive algorithms improve the feasibility of multi user receivers.