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In the title compound, C22H19ClN4, the pyrrole and pyrimidine rings form a dihetrocyclic fused pyrrolo-pyrimidine ring system which is almost co-planar; dihedral angle between two ring planes is 6.2º, to which five membered pyrrolidine ring is substituted, which is puckered to attain half chair conformation. Two other rings chloro-phenyl and phenyl are substituted at the 7 and 9 positions respectively in the fused ring system. Chloro-phenyl ring also shares the plane of fused ring system. (Dihedral angle between two ring system is 12.4º.) Crystal packing is stabilized due to ?-? interaction observed between pyrrole and chloro-phenyl ring of its symmetry related molecules (centroid-centroid distance: 3.8641 Å). Intramolecular C-H…N hydrogen bond is also observed in the molecular structure.

Takayasu's disease is an inflammatory arteritis particularly rare in children and is often difficult to diagnose due to the large clinical polymorphism and the absence of specific biological criteria. We report a rare case of takayassu disease revealed by pyoderma gangrenosum in a child. The diagnosis was confirmed by imaging, which showed multifocal arterial damage suggestive of vasculitis. 

Now-a-days the lots of accidents happen on highways due to increase in traffic and also due to a rash driving of the drivers. In many situations the family members or the ambulance and police authority is not informed in time. This result in delaying the help reached to the person suffered due to accident. The purpose of this paper is to find the vehicle where it is and locate the vehicle by means of sending a message using a system which is placed inside of vehicle system .Most of the times we may not be able to find accident location because we don’t know where accident will happen. Real Time Vehicle Accident Detection, Ambulance Rescue and Hospital Management System is designed to avoid such situations. This is an intension to implement an innovative solution for this problem.

In this era of information technology, computer has become indispensable in all fields, including Teaching of English as a Second Language. In India, the TESL has passed through various phases and methods involving technologies, though outdated today were popular then. This shows that throughout the ages, there was a constant search for a new method to realize the needs of the ESL learners. Recently, the concept of Second Language Acquisition has gained significance and linguists try various techniques to minimize the difference between First Language Acquisition and Second Language Learning. Once such method which makes the best use of scientific advancements in TESL research is Computer Assisted Language Learning (CALL).

In this paper, the application of the fully automated road detection for high resolution panchromatic images is proposed. This approach includes image binarization, boundary tracing algorithm and mathematical morphology reconstruction in order to retrieve main regions which have high potential to be regarded as road. Fuzzy C-means clustering is used for image binarization. Moore-Neighbour tracing algorithm modified by Jacob's stopping criteria is applied for tracking and labelling regions then flood-fill algorithm is exerted on regions in order to fill holes. Afterwards, four main shape-factors are introduced which can effectively discriminate between road and other terrain features. The R, H, Q and C factors that are relevant to shape of road are defined in this research. K-means cluster is then utilized to separate the roads from others, based on mentioned shape-factors. The algorithm has been tested with PANchromic (PAN) image of Worldview2 sensor. The results demonstrated development in road detection based on shape-factor clustering.

Organization culture is a set of values that defines what the organization stands for, how it works and what things or activities it considers important. The primary aim of this paper is to analyze the impact of organizational culture on employee satisfaction with respective to Pearl Beverages Limited, Guntur. . Percentage score analysis has been applied to meet the primary aim of this study. The paper argues that organizational culture significantly influences employee satisfaction and performance

This study attempts to investigate the change, if any, in the volatility observed in the Indian stock market due to the introduction of futures trading. The change in the volatility is compared in terms of the structure of the volatility. This is done to give insights into the way the futures market is influencing the Indian spot market’s volatility. The main objective of the study is to investigate whether there has been significant change in relative volatility of the underlying spot return and futures return. The period of study is from 1st January 2000 to 31st December 2010 for the spot prices. The study used three stock indices of NSE namely Nifty, CNX IT and CNX Bank. The index futures time series analyzed here uses data on the near month contract as they are most heavily traded. The study has used four measures of volatility. The study finds that for the three NSE indices, the study rejects the null hypothesis of ‘no significant change in relative inter-day volatility between spot prices and futures prices’ over the entire period 2000-2010, but cannot reject the hypothesis fully for all the individual years. There is significant change in relative intra-day volatility between spot prices and futures prices for all the three NSE indices.

Omeprazole is chemically 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl) methyl] sulfinyl ]-1H benzimidazole. It works by blocking acid production in the stomach. This medication is known as a proton pump inhibitor (PPI). It is used to treat acid-related stomach and throat (esophagus) problems and also used in the treatment of dyspepsia, peptic ulcer disease (PUD), Gastro esophageal reflux disease (GORD/GERD), and Laryngopharyngeal reflux (LPR) and Zollinger–Ellison syndrome. From the literature survey conducted there is no simple method reported for the determination of Omeprazole in capsule dosage form. Hence an attempt has been made to develop a HPLC method for the determination of Omeprazole is capsule dosage form and validate the developed method. The method was validated with respect to linearity, precision, system suitability, and specificity. The response was linear in concentration range of 9.6µg/ml to15.6µg/ml. The value of correlation coefficient found to be 0.9992. The R.S.D% value for repeatability precision studies was 0.8500. For system suitability it is essential for the assurance of the quality performance of chromatographic system so five injections of standard drug solution were given to the system. The %RSD value for system suitability was 0.1645.

The antibacterial activity of methanolic crude extract of Diacure, a polyherbal formulation was investigated against Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis, Micrococcus luteus, Escherichia coli and Candida albicans as test strains at different concentrations (80, 90 and 100?l/disc). Better antibacterial activity was observed with the extracts of diacure, that showed excellent inhibitory activity against Klebsiella pneumoniae, Escherichia coli and Candida albicans at concentration of 100 ?l/disc. Among different bacteria tested Klebsiella pneumoniae, Escherichia coli and Candida albicans were found to be more sensitive to crude extract when compared to others. HPLC analysis of the crude extract of diacure, a polyherbal formulation of 11 medicinal plants showed four different Phenolic acids (Tannic acid, Gallic acid, Ferulic acid and Caffeic acid). The results of the study provide scientific basis for the use of the plant extract in the future development as antioxidant, antibacterial, antifungal and anti-inflammatory agent.

Job rotation is a movement of employees from one job to another within the same organization and eventually returning to the original position. Job rotation enables employees to gain additional skills, knowledge and insight about the organization, this in turn helps the organization to fill future vacancies within the organization and reduce turnover. The study accessed the impact of job rotation on organizational performance at Unilever Ghana Limited using Tema branch as a case study. Both primary and secondary data were sourced for the study. The data collected were analyzed qualitatively using descriptive analysis like charts and tables. The major findings of the study were that Unilever Company Limited, Tema has a policy on job rotation and it’s been practiced. The practice of Job rotation in the Company had a moderate effect in helping the company’s performance. The recommendations are that, maximum productivity can be attained when employees are adequately and properly trained and motivated and management should handle issues by identifying and correcting errors, irregularities, personal collusion, safeguarding assets and maintaining a sustainable internal control system by implementing its policy on job rotation system.