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Platelets rich plasma (PRP) is reported to facilitate muscle regeneration both in vitro and animal studies. The aim of the study was to evaluate the intramuscular of PRP on growth factors and the regeneration of exercise induced muscle damaged (EIMD).Volunteers were assigned to a control (n=6) or PRP (n=6), and performed exhaustive exercise with one repetition maximum (1RM-80%) maximal voluntary contraction of the elbow. The arms were treated with saline or PRP post-24h exercise and blood samples were obtained in the morning to establish a baseline value and also 1-4 days post-exercise. The baseline levels of plasma insulin-like growth factor 1(IGF-1), insulin-like growth factor-binding protein 3 (IGFBP-3), vascular endothelial growth factor (VEGF) were different whilst growth hormone (GH) and platelet-derived growth factor (PDGF-BB) levels were similar in both groups. However, 24 h following exercise increased levels of IGF-1, GH and IGFBP-3 in control were observed. PRP up-regulated PDGF-BB and VEDF, it also inhibited GH, IGF-1 and IGFBP-3 levels post-exercise.

Enzymatic potentials of thermo-tolerant bacteria from waste dumpsites were analyzed. 30 soil samples were collected using sterile spatular into sterile universal bottles, labelled and taken to the laboratory analyses. The soil samples were serially diluted and inoculated by spread plate method on different media and incubated at 30oC for 48 hrs. The pure isolates were stored in agar slants in the refrigerator for further use. Isolates with thermophilic ability were screened for amylase, protease and lipase activity. Effects of temperature and pH on enzyme activity of the thermophilic bacterial isolates were also assessed. Bacillus subtilis (70.0%), Bacillus licheniformis (43.3%), Bacillus cereus (56.7%), Pseudomonas aeruginosa (56.7%), Streptomyces species (36.7%), Bacillus brevis (43.3%) and Norcadia species (30%) were isolated from the soil samples. All the bacterial isolates tolerated 55oC temperature while only Bacillus cereus, Bacillus brevis and Norcadia species were isolated at 60oC. All the isolates except Pseudomonas aeruginosa gave amylase activity while all the isolates gave protease activity. All the isolates except Bacillus licheniformis and Nocardia species showed lipase activity. Temperature and pH had varied effects on the enzyme activity of the isolates. These bacteria are good sources of enzymes at thermophilic temperatures and varied pH for commercial use.

Table of contents for the month of January 2020

Much has been said about the Universalism of Chomsky and his so-called revolutionary theories in the field of Modern Linguistics, but little has been done in the way of bringing in line the roots, origins and the historical bases of such a bundle of theories with Modern Western Literary Movements and the way they go back to their historical, cultural and literary tradition in describing their philosophy and assumptions. To be more specific, the present study intends to carry out a comparative study between New Criticism- as the first modern Anglo-American school of criticism- and Chomsky’s Universalism, by going to deeper levels of their priori and structure in an attempt to find a common background, as they both owe much to the heritage from which they emerge: the Old Western Tradition of Philosophy.

Mentoring is a relationship between an experienced person and a less experienced person for the purpose of helping the one with less experience. The mentee seeks the advice and support of the more experienced person. Coaching is the way in which people with vast experience help those in the same job or field of endeavor who have less experience. Coaching usually deals with specific skills and tactics, while mentoring often is a long-term process and a more personal relationship is formed. In both coaching and mentoring the goal is to help people to reach their full potential. In a basic sense it is a method of training, directing or instructing a person or group of people to do a specific task, achieve a goal or develop certain skills. Coaches are usually paid for their work, and their relationship with those being coached is a professional one. In this paper I would like to discuss various aspects of Mentoring and Coaching for the development of employees in the organization.

Utility mining is to discover the itemsets in a transaction database with utility values over a given threshold. Utility of itemsets are based upon user’s perception such as cost, profit or revenue and are of significant importance. Utility-based data mining intends discovering the itemsets with high total utility is called High Utility Itemset mining. High Utility itemsets may contain frequent as well as rare itemsets. Classical utility mining considers items alone as discrete values. In real world applications, such utilities can be described by fuzzy sets. In this paper, proposed an algorithm, FHUI (Fuzzy High Utility Itemset) Mining is presented to mine high utility itemsets effectively from large databases, by fuzzification of utility values. FHUI extracts fuzzy high utility itemsets by integrating fuzzy logic with high utility itemset mining. This algorithm finds all utility-frequent itemsets within given threshold value. The experimental result shows that, it performs efficiently in terms of speed and memory on large databases.

Combined free and forced convection flow in a vertical channel filled with porous and fluid layer is studied with boundary conditions of third kind. The flow is modeled using Brinkman model. The viscous and Darcy dissipation terms are also included in the energy equation. The plate exchanges heat with an external fluid. Separate solutions are matched at the interface using suitable matching conditions. The coupled non-linear governing equations are solved using perturbation series method valid for small values of the perturbation parameter. The condition for perturbation parameter is relaxed by finding the solutions of the governing equations using Differential Transform method. The effects of various parameters on the flow such as mixed convection parameter, porous parameter, viscosity ratio, width ratio, conductivity ratio and Biot numbers on the flow are explored graphically. Further it is also shown that the Differential Transform method solutions agree very well with perturbation method series solutions for small values of the perturbation parameter.

The construction of complex model of titan-magnetite granule formation of powdered materials in drum granulators taking into account of anisotropy of structure and laminating on surface is considered. It has been noted that granule formation proceeds in some stages depending on relaxation time of embryo formation. On the base of model a graphic interpretation of process of laminating of powder on surface is cited. Rheological model of compact of granules under action of external deformation stresses allowing to estimate the change of porosity and density in time of arrive is presented. The comparison of calculation and experimental results for evolution of distribution of granules on sizes has been presented.

Entrepreneurship is the professional application of knowledge, skills and competencies and/or of monetizing a new idea, by an individual or a set of people by launching an enterprise. Given the increasing significance and visible impact of Entrepreneurship in wealth-creation and employment-generation, entrepreneurship is considered as critical to India’s growth and development (NKC-2008). This study was undertaken to explore factors that have advanced Entrepreneurship in youth of India. The paper highlights the perception of youth towards entrepreneurship as a career. The paper also points out the realities of gap between students’ learning about entrepreneurship in B-schools and ending up being entrepreneurs.

Nickel is a metal of widespread distribution in the environment: there are almost 100 minerals of which it is an essential constituent and which have many industrial and commercial uses. Nickel and nickel compounds belong to the classic noxious agents encountered in industry but are also known to affect non-occupationally exposed individuals. The general population may be exposed to nickel in the air, water and food. Inhalation is an important route of occupational exposure to nickel in relation to health risks. Most nickel in the human body originates from drinking water and food; however, the gastrointestinal route is of lesser importance, due to its limited intestinal absorption. The toxicity and carcinogenicity of some nickel compounds (in the nasal cavity, larynx and lungs) in experimental animals, as well as in the occupationallyexposed population, are well documented. The objective of this paper is to summarize the current overview of the occurrence and sources of nickel in the environment, and the effect of this metal and its compounds on living organisms.