Archives-July 2013

The skin biopsy is an important diagnostic tool in dermatology because it establishes a definite diagnosis and also monitors the therapy in many systemic diseases. The microscopic features involving superficial inflammatory dermatitis are very similar, but treatment varies, hence the diagnosis of the skin biopsy requires meticulous, clinical and histopathological work up. One hundred and fifty one consecutive skin biopsy specimens where a superficial inflammatory dermatosis has been queried by Dermatologists are reviewed. The lesions of superficial inflammatory dermatosis are classified based on the integration of different morphological features into three types of tissue reactions ie. Spongiotic dermatitis, lichenoid dermatitis and psoriasiform dermatitis. Histopathological diagnosis is concluded after coorelating with clinical features, which either confirms, contributes or noncontributory to the clinical diagnosis. The study revealed that the Psoriasiform Dermatitis is the most frequently encountered about 46.0%, followed by the lichenoid Dermatitis 27.2% and Spongiotic Dermatitis 16.6%. The clinico-histopathological discrepancy between few cases like Dermatitis Herpetiformis & Prurigo Simplex, Polymorphous light eruption & Leprosy, Hypertrophied Lichen Planus & Prurigo nodularis, Mycosis Fungoides & Exfoliative Dermatosis is discussed in detail. Correlation of the histopathological diagnosis with clinical diagnosis is seen in 95.6% cases of Psoriasiform Dermatitis, 92.87% cases of Lichenoid Dermatitis and in 92.3% of cases of Spongiotic Dermatitis. The present study also contributed that the histopathological diagnosis is confirmatory, diagnostic or non-contributory in 90.6%, 4.6% and 4.8% cases respectively to the clinical diagnosis. This article thus emphasizes the importance and utility of classification of superficial inflammatory dermatosis. The data showed the distribution of the lesions in three categories was helpful in reducing the number of inconclusive biopsies.

In this paper, we study the variation of the convergence speed on basis of the local search method used in a memetic algorithm (MA); for this reason we compared two memetic algorithms MA1 and MA2 implemented with two different local search methods are descent and simulated annealing successively applied to the scheduling tasks problem. Then we will make a comparison between these two algorithms (MA1, MA2) results, with the genetic algorithm and other metaheuristics previously used to solve the same problem to get an idea on the most efficient methods in term of completion time work for this problem and choose the most effective.

The Baylis-Hillmann reaction of 8-formyl-7-hydroxy furyl chromones on react with Acrylonitrile in DABCO/CHCl3 medium under nitrogen atmosphere at room temperature gives of 2-(2-furyl)-3-methyl-4oxo-4H,8H-pyrano[2,3-f]chromene-9-carbonitrilies (4a-h) in good yields.

Three water sample in Oghara Community, Ethiope -West, Nigeria were assessed for Physico-Chemical and heavy metals. The pH of the water ranges from 6.10-8.60, conductivity of water lies between 7.50-77.90?/cm. Total solids, Total alkalinity, hardness, sulphate, ranges from 40.00-50.00mg/1, 28.00-29.70mg/l, 37.00-4.00mg/1, 55.20-5.30mg/I respectively, copper, iron, zinc lies between 0.02 – 0.03mg/I, 0.07-0.08mg/I, 021-0.31mg/I respectively. The results obtained from this study fall within the recommended values specified by NAFDAC and SON except the pH from site C that was above the maximum permissible limits specified by National Agency for Food Drug Administration and Control. (NAFDAC) and Standard Organization of Nigeria (SON).

The primary objective was to evaluate if batch staining of malaria blood films results in false positive smears. False positive smears (>1%) may cause a serious underestimate of a drug’s or vaccine’s protective efficacy, as well as affect evaluation of diagnostics, estimates of malaria prevalence, and clinical management. Thick blood films may float from a glass slide during staining and adhere to other films if batch staining is used resulting in false positive readings. Venous blood in EDTA anticoagulant from malaria positive samples of ? 20 parasites per high power field and a true negative sample was utilized to make thick and thin smears. Two true negative smears were stained with Giemsa stain with eight positive smears in batch in Coplin jars for 10 minutes or overnight. Two control negatives were stained alone with the same batch of stain. Blinded microscopists read these slides using a rereading paradigm. Thick film loss was graded by gross appearance ranging from 0 (none) to 4+ (> ¾ loss). A total of 602 slides were evaluated in this study, of which 392 were true positives (65%) and 210 (35%) were true negatives. Of the true negatives, 110 were batch stained with true positives, and 100 were true negative controls stained alone. Of the initial readings, 11-20% were reported falsely positive. “Fishing” or cross-contamination was infrequently noted by one of the microscopists, but was uniformly present in these smears on reexamination. Of the true positive smears (high density), 1-3% were read falsely negative. On reexamination of these slides, the cause was found to be reporting of results from very poor quality smears. Thick film loss was clearly more severe for the positive slides with 10 minute versus overnight drying (means score 0.97 vs 1.97, p <0.001).

Two problems often crop up in adaptive sampling. One, it may not be feasible to sample according to a designated sampling plan. And two, the prescribed sampling plan may result in very small selection probabilities for some units thereby giving large weights to such units in estimation. In order to ameliorate these problems, a regression procedure that combines design and model-based techniques of estimation is proposed. Adaptive sampling designs are designs in which additional units or sites for observation are selected depending on the interpretation of observations made during initial sampling. Additional sampling is driven by the observed results from an initial sample. The results from this study demonstrate that the existing Horvitz-Thompson estimator for adaptive cluster sampling can be improved using model assistance.

The Ministry of Corporate Affairs has introduced the MCA21 e-Governance programme with a view to providing all services relating to ROC offices on-line in e-Governance mode.MCA21 replaces the erstwhile practices broadly consisting of physically filing of documents, incorporation of companies and inspection of documents with the Registrar of Companies. This project is the first of its kind and is intended to create a health business eco system conducive to foreign investment thereby boosting the Indian economy. This paper investigate whether the goals of the project i.e to improve the service standards to all the stakeholders have been achieved or not ?what are the new amendments in MCA project and how it is beneficial to all the stakeholder?. The analysis shows that among other e-governance programmes MCA 21 is the one which have a positive impact on the user and day by day its importance is increasing .It does not include other offices like Liquidators , CLB(Company Law Board)/Tribunals and Courts. Many up gradations were done in MCA 21 project like –XBRL,NEFT but still there is a need for increasing the awareness about use of online procedures relating to MCA and improvement in website facility during peak season.

Resources hub NCBI and EBI with databases like KEGG, METACYC etc. were used for computational comparative analysis of metabolic pathways in E.coli and A. thaliana to determine common enzymes and motifs according to same EC number. The extent of conservation in the metabolic pathways like glycolysis, citrate pathway, pyruvate pathway, nucleotide sugar pathway, riboflavin pathway, carboxylate pathway, galactose pathway, methane pathway, urea pathway and pentose phosphate pathway present in both E.coli and A. thaliana was analyzed. Among the ten metabolic pathways shared by both organisms, seven enzymes were identified in pentose phosphate pathway of both organisms according to their EC number. Nine motifs were present in methane pathway and nucleotide sugar pathway of E. coli. In A. thaliana maximum eight motifs in methane pathway and one in each pentose phosphate pathway, riboflavin pathway and urea pathway was identified. Comparison of E. coli and A. thaliana metabolic pathways shows that central set of pathway is largely conserved in terms of pathways, domain architect and motifs present. There was difference in the position of the motifs present in the enzymes that perform the same function so the variation in the stretch of amino acid conferring a specific structure needs to be distinguished.

This research is an attempt to study the supervision system of elementary school teachers in Kermanshah Province in order to develop a conceptual framework applying a descriptive-method. To do these first 176 factors were derived through studying the literature of models and theories in Iran which resulted in 93 factors after surgery. The suggested framework includes five main categories: philosophy and objectives, theoretical principals, supervision functions, operation stages and the model's evaluation system. The statistical community of this survey includes all teachers of Kermanshah elementary schools of which 384 teachers have been selected based on multi stage grape sampling. The content of the questionnaires developed based on educators suggestions about the content and analysis of factors and necessary modifications applied. The stability of the questionnaires has been estimated by Krenbach's Alpha method in a desirable value of 0.901. For evaluating the validity of the model 30 scholars have been selected. For data analysis descriptive statistics were applied. The main findings are: 1. in studying the current situation of the teachers' supervision system, the factors of class management and the school regulations had better results than other factors. In the factor of evaluation from the students learning the performance was average but in sustainable development of educational quality, teacher professional development and commitment, motivating students, determining educational and curricular objectives, teacher performance evaluation less work has been carried out. And in analysis of the factors, the factors classification has changed from seven to 13 factors. 2. Developing a suggested framework in order to study the teacher supervision including five categories of philosophy and objectives, theoretical principals, supervision functions in 13 branches, operation stages, and evaluation system. 3. The findings from validity of questionnaires from scholars indicate a 91.78% suitability ranking by the scholars which shows a high validity of the model in the eyes of the scholars.

The job- employed fit is one of fundamental issues in human resource management. It has been improved that, this fit is an organizational necessity for the human source profitability. So, the main aim in this research is to investigate the job- employed fit and the effects on female personnel's emotional intelligence among governmental organizations in Kermanshah. This research is conducted based on descriptive and surveying method; the instruments to collect data include queries; the Salovey & Mayer standard emotional intelligence query is used to investigate the emotional intelligence; and the knowledge, skill and ability queries from international Occupational Information Network (O*NET) are implemented to investigate the job- employed fit, and each query includes, in average, 21 questions. The perpetuity was 0/79 for emotional intelligence query and 0/81 for job- employed fit query and because the Cronbach ? is more than 0/7 for both queries, therefore both queries has enough perpetuity. The considered statistical society includes 300 female personnel from governmental organizations in Kermanshah. Based on random sampling method, some category was selected as statistical sample, and 156 queries were collected, finally. We used Colmogrov- Smirnov test to determine the data normality and the results gained from the test supported it; the research theories were tested using absolute T-test and some positive and considerable effect was demonstrated. The results show that in considered society, the job- fit personnel gain higher emotional intelligence scores. Another result gained in this research indicated that just 40% of female personnel are completely job- fit and therefore these organizations have an unstable situation.